one thing you could try is downloading and running the fantastic A-squared antispyware program, I find this program will usually pick up a few things that all the others miss as it uses an entirely different scanning engine. there is a free and paid version available. Also Simply super Softwares Trojan remover is another good and legit program to use. I am not sure if they gave a free version but i am sure a quick search on google will find that. This program helped me out last year when i got hammered by a virus and all my other programs didn't find it but trojan remover did and removed it and fixed my system without having to reformat. Good luck mate i know how frustrating it can be when you get a virus but perservere and you should be able to win this battle

One suggestion would be is if you know when the computer started messing up is to restore to a date before that. 

I'm sure that there are other programs to run to try and clean the computer of virus/malware/trojans but you may not find everything.

The only other alternative is one that I'm pretty sure you have thought about, reformat the harddrive  and do a clean install of the OS.

Good luck.

www.emsisoft.com/en/software/free/

and it is free.

Have you tried in safe mode and at boot up?

Just for information and not that it's going to solve your situation. Comcast doesn't offer McAfee anymore and it will expire very soon if it hasn't already. If you have Comcast you now get the full Norton Security Suite 360. If you go for it of course you would have to delete McAfee first.

http://security.comcast.net/ 

Hey guys thanks for all the responses.  For right now I can try the free anti-virus scanners.  Thanks for the suggestions Nimbin and DrJBHL.

Thanks for the advice on restore points Philly0381 but, restore points were turned off on this machine. We tried that and it is a nogo.

Thanks for the advice w4xpl4y3r.  I tried that once earlier but, I had difficulty getting Windows to run in Safe Mode.  It just kept looping back to the Windows startup selection screen(B&W screen).  I'll try that again. 

Are there any really good free online scanners which will also remove any viruses found??

Loaris Trojan Remover

http://www.softpedia.com/get/Antivirus/Loaris-Trojan-Remover.shtml

Reformat.

Thanks for the link DaveBax that will be done next week.

Thanks for the link machanix76.

Hi Jafo!!  You might be right, this one has been impossible to defeat so far.  The Norton free online scurity scan I went to from the Comcast Security web page came up blank also.

Sounds like a virus that I had a couple of years ago. The damn thing kept backing itself up and I had to break down and reformat. Luckily the computer was only a week old, so it wasn't a huge loss.

Good luck to ya!

If you do decided to reformat then think about how you want to set up the computer as fas as security goes.  Turning on the restore points function might be a start and then establishing a restore point after doing scheduled clean up and running scans would be good. 

I am now posting a HijackThis log on Bleeping Computer web site.  I hope this works.

Should...

Dump just about anything that says 'BHO'....that'll help.

Reality is tho that Browser Hijackers can be a pain in the bum to chase down/remove....As Ripley said..."Dust off and nuke them from space....only way to be sure."

aka

Reformat....

As Paul said........Your safest option is to reformat...........Ask yourself..........are you ever going to be really sure that the virus has gone even after additional scanning??? If the answer is 'no'.............always reformat and then it will definately be gone.............If you want to go the free scanner route use BOTH the on-line tools offered by Kaspersky and ESET (two of the better known and reliable products) and they will give your machine a thorough going over. Links:-

Kasperskys on-line scanner is awol at the moment undergoing an overhaul but you can check individual files here  http://www.kaspersky.com/scanforvirus

ESET http://www.eset.com/online-scanner

..........But reformat is your best option

Ditto with the reformat,one more thing & it's free, macrium reflect it's an imaging program,only point i need to make is you need to create one time images (not to be confused with cloning as that's the whole hard drive including partitions),also it pays to have two copies of an image on seperate hdd's & take the images as you go starting from initial install

http://www.macrium.com/reflectfree.asp

CNET,PCWorld are good places to get free securityware

You also might want to consider using something like returnil or sandboxie

EDIT:Forgot to mention spywareterminater,it's pretty much the same as SUPERantispyware (or however it's spelt) except you get full funtionality & with HIPs enabled nothing can install without your knowledge

these nasty little morons who create these trojans etc shld be shot - they are not harming microsoft but ordinary ppl. i have had to do fresh installs before and it is a time wasting pain

Well...before reformatting...Have you considered using Firefox instead of the slow and dangerous IE8? Seems that the problem is IE related and it's a good chance to dump it for good and enjoy much faster and safer browsing!

If you like to be even safer, you can install AdBlockPlus and No-Script add-ons (for Firefox) to stop malicious code.

If that doesn't help, no need to give-up before you tried installing few free antivirus programs (but you'll have to uninstall the current one every time). Try Avast and Avira at least!

Wow thanks everyone for the great advice.  I'm limited with what options I can apply to this pc, it is state property.  Because I've been helpful with past problems, I'm being allowed to work on this one. 

I'll try the Kaspersky and Eset online scanning links next.  Thanks Leo the Lion. 

I'll take this one step at a time.  Eventually the culprit will be found. 

Does anyone know why this Dell Optiplex Pentium 4 computer won't boot into Safe mode?  Windows fails to boot in safe mode then it loops back to loading the bios and Windows startup selection screen (F8 key).

Wouldn't be surprised if that was down to the 'infection' too....nothing better than crippling one of the methods of infection resolution...

And after you go through the reformat process...do yourself a huge favor and get Acronis True Image home and then when you have your fresh bare bones install back it all up...then install all your apps and back that up as well. Then when you get those nasty viruses you'll have to choices to backup to. And the nice thing is...click it and walk away.